Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer

Telomerase reactivation is a hallmark of human carcinogenesis. Increased telomerase activity may result from gene amplification and/or overexpression. This study evaluates the prognostic value of hTERT gene amplification and mRNA overexpression in 144 resectable non-small-cell lung cancer (NSCLC) sp...

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Detalhes bibliográficos
Main Authors: Zhu, C-Q, Cutz, J-C, Liu, N, Lau, D, Shepherd, F A, Squire, J A, Tsao, M-S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361293/
https://ncbi.nlm.nih.gov/pubmed/16641908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603110
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