The Wnt antagonist sFRP1 is downregulated in premalignant large bowel adenomas

Our previous studies have implicated the Wnt antagonist, sFRP1, as a tumour suppressor gene in advanced colorectal cancer. In this study, we set out to investigate the relationship between sFRP1 expression and large bowel adenomas, a precursor of colorectal cancer. The induction of β-catenin/TCF med...

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Bibliografiske detaljer
Main Authors: Caldwell, G M, Jones, C E, Taniere, P, Warrack, R, Soon, Y, Matthews, G M, Morton, D G
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
Fag:
Genetics and Genomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361362/
https://ncbi.nlm.nih.gov/pubmed/16523202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602967
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