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Malignant melanoma and bone resorption

The cellular and humoral mechanisms accounting for osteolysis in skeletal metastases of malignant melanoma are uncertain. Osteoclasts, the specialised multinucleated cells that carry out bone resorption, are derived from monocyte/macrophage precursors. We isolated tumour-associated macrophages (TAMs...

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Bibliografiske detaljer
Main Authors: Lau, Y S, Sabokbar, A, Giele, H, Cerundolo, V, Hofstetter, W, Athanasou, N A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361270/
https://ncbi.nlm.nih.gov/pubmed/16641914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603103
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