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Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma

Cellular mechanisms that account for tumour osteolysis associated with Ewing's sarcoma are uncertain. Osteoclasts are marrow-derived multinucleated cells (MNCs) that effect tumour osteolysis. Osteoclasts are known to form from macrophages by both receptor activator for nuclear factor-κB (RANK)...

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Autors principals: Lau, Y S, Adamopoulos, I E, Sabokbar, A, Giele, H, Gibbons, C L M H, Athanasou, N A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359921/
https://ncbi.nlm.nih.gov/pubmed/17533390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603774
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