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Clinicopathological significance of mitochondrial D-Loop mutations in head and neck carcinoma

Mitochondrial DNA mutations have been reported in several types of tumours, including head and neck squamous cell carcinoma (HNSCC). The noncoding region of the Displacement-Loop (D-Loop) has emerged as a mutational hotspot and we recently found that they were associated with prognosis and response...

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Autors principals: Lièvre, A, Blons, H, Houllier, A M, Laccourreye, O, Brasnu, D, Beaune, P, Laurent-Puig, P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361200/
https://ncbi.nlm.nih.gov/pubmed/16495928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602993
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