Sex-dependent Association of a Common Low Density Lipoprotein Receptor Polymorphism with RNA Splicing Efficiency in the Brain and Alzheimers Disease

Since apoE allele status is the predominant Alzheimers disease (AD) genetic risk factor, functional single nucleotide polymorphisms (SNP)s in brain apoE receptors represent excellent candidates for association with AD. Recently, we identified a SNP, rs688, as modulating the splicing efficiency of lo...

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Hlavní autoři: Zou, Fanggeng, Gopalraj, Rangaraj K., Lok, Johann, Zhu, Haiyan, Ling, I-Fang, Simpson, James F., Tucker, H. Michael, Kelly, Jeremiah F., Younkin, Samuel G., Dickson, Dennis W., Petersen, Ronald C, Graff-Radford, Neill R., Bennett, David A., Crook, Julia E., G.Younkin, Steven, Estus, Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361153/
https://ncbi.nlm.nih.gov/pubmed/18065781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddm365
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