Monocytes and neutrophils as ‘bad guys’ for the outcome of interleukin-2 with and without histamine in metastatic renal cell carcinoma – results from a randomised phase II trial

Histamine (HDC) inhibits formation and release of phagocyte-derived reactive oxygen species, and thereby protects natural killer (NK) and T cells against oxidative damage. Thus, the addition of histamine may potentially improve the efficacy of interleukin-2 (IL-2). We have explored this potential me...

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Bibliografske podrobnosti
Main Authors: Donskov, F, Hokland, M, Marcussen, N, Torp Madsen, H H, von der Maase, H
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2006
Teme:
Clinical Study
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361121/
https://ncbi.nlm.nih.gov/pubmed/16434984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602937
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