Two randomised phase II trials of subcutaneous interleukin-2 and histamine dihydrochloride in patients with metastatic renal cell carcinoma

Histamine inhibits formation and release of phagocyte-derived reactive oxygen species, and thereby protects natural killer and T cells against oxidative damage. Thus, the addition of histamine may potentially improve the efficacy of interleukin-2 (IL-2). Two randomised phase II trials of IL-2 with o...

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Dettagli Bibliografici
Autori principali: Donskov, F, Middleton, M, Fode, K, Meldgaard, P, Mansoor, W, Lawrance, J, Thatcher, N, Nellemann, H, von der Maase, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2005
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361635/
https://ncbi.nlm.nih.gov/pubmed/16136045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602768
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