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Polymorphisms of glutathione S-transferases (GST) and thymidylate synthase (TS) – novel predictors for response and survival in gastric cancer patients

To evaluate the predictive value of a panel of gene polymorphisms involved in metabolism of 5-FU and cisplatin on clinical outcome in advanced gastric cancer patients. A total of 52 patients were enrolled in this study. DNA was extracted from paraffin-embedded tumour specimen. Genotypes were determi...

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Main Authors: Goekkurt, E, Hoehn, S, Wolschke, C, Wittmer, C, Stueber, C, Hossfeld, D K, Stoehlmacher, J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361118/
https://ncbi.nlm.nih.gov/pubmed/16317430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602891
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