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11q13 amplification status and human papillomavirus in relation to p16 expression defines two distinct etiologies of head and neck tumours
Two distinct etiologies of head and neck squamous cell carcinoma (HNSCC) have been proposed, DNA damage owing to tobacco and alcohol exposure and human papillomavirus (HPV) oncogene-mediated transformation. Common genetic alterations in HNSCC include TP53 mutations, 11q13 amplification (amp) and CDK...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360598/ https://ncbi.nlm.nih.gov/pubmed/17003776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603394 |
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