Efficient loading of dendritic cells following cryo and radiofrequency ablation in combination with immune modulation induces anti-tumour immunity

Dendritic cells (DC) are professional antigen-presenting cells that play a pivotal role in the induction of immunity. Ex vivo-generated, tumour antigen-loaded mature DC are currently exploited as cancer vaccines in clinical studies. However, antigen loading and maturation of DC directly in vivo woul...

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Detalhes bibliográficos
Main Authors: den Brok, M H M G M, Sutmuller, R P M, Nierkens, S, Bennink, E J, Frielink, C, Toonen, L W J, Boerman, O C, Figdor, C G, Ruers, T J M, Adema, G J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360548/
https://ncbi.nlm.nih.gov/pubmed/16953240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603341
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