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An α-fetoprotein-derived peptide reduces the uterine hyperplasia and increases the antitumour effect of tamoxifen

Tamoxifen (Tam) is effective for the treatment and prevention of breast cancer. However, it has toxic drawbacks and has limited-duration utility because, over time, human tumours become refractory to Tam. Recently, a new nontoxic peptide, α-fetoprotein-derived peptide (AFPep) has been proposed for t...

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Bibliografski detalji
Glavni autori: Andersen, T T, Georgekutty, J, DeFreest, L A, Amaratunga, G, Narendran, A, Lemanski, N, Jacobson, H I, Bennett, J A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360332/
https://ncbi.nlm.nih.gov/pubmed/17637684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603882
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