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The hollow fibre assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells

The Hollow Fibre Assay (HFA) is usually applied as an early in vivo model for anti-cancer drug screening, but is potentially an excellent model for short-term in vivo pharmacodynamic studies. We used the model to study the in vivo role of thymidine phosphorylase/platelet-derived endothelial cell gro...

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Bibliografiske detaljer
Main Authors: Temmink, O H, Prins, H-J, van Gelderop, E, Peters, G J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360204/
https://ncbi.nlm.nih.gov/pubmed/17179993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603507
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