Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy

The predictive value of KRAS mutation in metastatic colorectal cancer (MCRC) patients treated with cetuximab plus chemotherapy has recently been suggested. In our study, 59 patients with a chemotherapy-refractory MCRC treated with cetuximab plus chemotherapy were included and clinical response was e...

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Detalhes bibliográficos
Main Authors: Di Fiore, F, Blanchard, F, Charbonnier, F, Le Pessot, F, Lamy, A, Galais, M P, Bastit, L, Killian, A, Sesboüé, R, Tuech, J J, Queuniet, A M, Paillot, B, Sabourin, J C, Michot, F, Michel, P, Frebourg, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360149/
https://ncbi.nlm.nih.gov/pubmed/17375050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603685
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