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Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer

Since 2004, the clinical impact of monoclonal antibodies (mAbs) targeting the epidermal growth factor receptor (EGFR) on patients with metastatic colorectal cancer (MCRC) has been clearly established. The combination of these biological agents with conventional chemotherapy has led to a significant...

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Bibliografiske detaljer
Main Authors: Di Fiore, F, Sesboüé, R, Michel, P, Sabourin, J C, Frebourg, T
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008616/
https://ncbi.nlm.nih.gov/pubmed/21139621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6606008
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