The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome

EphB4 is a member of the largest family of transmembrane receptor tyrosine kinases and plays critical roles in axonal pathfinding and blood vessel maturation. We wanted to determine the biological role of EphB4 in ovarian cancer. We studied the expression of EphB4 in seven normal ovarian specimens a...

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Bibliographic Details
Main Authors: Kumar, S R, Masood, R, Spannuth, W A, Singh, J, Scehnet, J, Kleiber, G, Jennings, N, Deavers, M, Krasnoperov, V, Dubeau, L, Weaver, F A, Sood, A K, Gill, P S
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
Subjects:
Translational Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360128/
https://ncbi.nlm.nih.gov/pubmed/17353927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603642
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