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hEGR1 is induced by EGF, inhibited by gefitinib in bladder cell lines and related to EGF receptor levels in bladder tumours

The effect of EGF and gefitinib on two EGFR-positive human bladder cancer cell lines has been investigated using array-based gene expression profiling. The most prominent transcript, increased up to 6.7-fold by EGF compared with controls in RT112 cells, was human early growth response protein 1 (hEG...

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Detalhes bibliográficos
Main Authors: Nutt, J E, Foster, P A, Mellon, J K, Lunec, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360087/
https://ncbi.nlm.nih.gov/pubmed/17311025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603620
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