In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer

Promoter hypermethylation is central in deregulating gene expression in cancer. Identification of novel methylation targets in specific cancers provides a basis for their use as biomarkers of disease occurrence and progression. We developed an in silico strategy to globally identify potential target...

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Main Authors: Perry, A S, Loftus, B, Moroose, R, Lynch, T H, Hollywood, D, Watson, R W G, Woodson, K, Lawler, M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Genetics and Genomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359953/
https://ncbi.nlm.nih.gov/pubmed/17453001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603767
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