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Characterisation of the anti-apoptotic function of survivin-ΔEx3 during TNFα−mediated cell death

Survivin is an oncogenic protein involved in cell division and acts as an anti-apoptotic factor. It is highly expressed in most cancers and is associated with chemotherapy resistance, increased tumour recurrence, and shorter patient survival. This makes anti-survivin therapy an attractive cancer tre...

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Detalhes bibliográficos
Main Authors: Malcles, M-H, Wang, H-W, Koumi, A, Tsai, Y-H, Yu, M, Godfrey, A, Boshoff, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359927/
https://ncbi.nlm.nih.gov/pubmed/17505517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603768
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