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Unusually rapid evolution of Neuroligin-4 in mice

Neuroligins (NLs) are postsynaptic cell-adhesion molecules that are implicated in humans in autism spectrum disorders because the genes encoding NL3 and NL4 are mutated in rare cases of familial autism. NLs are highly conserved evolutionarily, except that no NL4 was detected in the currently availab...

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Detalles Bibliográficos
Main Authors: Bolliger, Marc F., Pei, Jimin, Maxeiner, Stephan, Boucard, Antony A., Grishin, Nick V., Südhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359808/
https://ncbi.nlm.nih.gov/pubmed/18434543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801383105
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