Synergistic effects of high fat feeding and apolipoprotein E deletion on enterocytic amyloid-beta abundance

BACKGROUND: Amyloid-β (Aβ), a key protein found in amyloid plaques of subjects with Alzheimer's disease is expressed in the absorptive epithelial cells of the small intestine. Ingestion of saturated fat significantly enhances enterocytic Aβ abundance whereas fasting abolishes expression. Apolip...

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Bibliografiska uppgifter
Huvudupphovsmän: Galloway, Susan, Pallebage-Gamarallage, Menuka MS, Takechi, Ryusuke, Jian, Le, Johnsen, Russell D, Dhaliwal, Satvinder S, Mamo, John CL
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2008
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359747/
https://ncbi.nlm.nih.gov/pubmed/18426603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-7-15
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