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Synergistic effects of high fat feeding and apolipoprotein E deletion on enterocytic amyloid-beta abundance

BACKGROUND: Amyloid-β (Aβ), a key protein found in amyloid plaques of subjects with Alzheimer's disease is expressed in the absorptive epithelial cells of the small intestine. Ingestion of saturated fat significantly enhances enterocytic Aβ abundance whereas fasting abolishes expression. Apolip...

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Bibliografische gegevens
Hoofdauteurs: Galloway, Susan, Pallebage-Gamarallage, Menuka MS, Takechi, Ryusuke, Jian, Le, Johnsen, Russell D, Dhaliwal, Satvinder S, Mamo, John CL
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359747/
https://ncbi.nlm.nih.gov/pubmed/18426603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-7-15
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