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Empirical Bayes models for multiple probe type microarrays at the probe level

BACKGROUND: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are adjusted towards a global estimate, producing more stable results compared to ordinary t-tests. However, for Affymetrix...

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Detalhes bibliográficos
Main Authors: Åstrand, Magnus, Mostad, Petter, Rudemo, Mats
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2358895/
https://ncbi.nlm.nih.gov/pubmed/18366694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-156
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