Sperm-derived histones contribute to zygotic chromatin in humans

BACKGROUND: about 15% to 30% of the DNA in human sperm is packed in nucleosomes and transmission of this fraction to the embryo potentially serves as a mechanism to facilitate paternal epigenetic programs during embryonic development. However, hitherto it has not been established whether these nucle...

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Autors principals: van der Heijden, Godfried W, Ramos, Liliana, Baart, Esther B, van den Berg, Ilse M, Derijck, Alwin AHA, van der Vlag, Johan, Martini, Elena, de Boer, Peter
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2358879/
https://ncbi.nlm.nih.gov/pubmed/18377649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-8-34
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