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Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

In the majority of cervical cancers, DNAs of high-risk mucosotpropic human papillomaviruses (HPVs), such as type 16, are maintained so as to express two viral proteins, E6 and E7, suggesting an essential importance to carcinogenesis. The high-risk HPV E6 proteins are known to inactivate p53 tumor su...

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Autors principals: Kiyono, Tohru, Hiraiwa, Atsuro, Fujita, Masatoshi, Hayashi, Yasuyuki, Akiyama, Tetsu, Ishibashi, Masahide
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23554/
https://ncbi.nlm.nih.gov/pubmed/9326658
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