Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

In the majority of cervical cancers, DNAs of high-risk mucosotpropic human papillomaviruses (HPVs), such as type 16, are maintained so as to express two viral proteins, E6 and E7, suggesting an essential importance to carcinogenesis. The high-risk HPV E6 proteins are known to inactivate p53 tumor su...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kiyono, Tohru, Hiraiwa, Atsuro, Fujita, Masatoshi, Hayashi, Yasuyuki, Akiyama, Tetsu, Ishibashi, Masahide
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23554/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11612
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