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Identification of the prooxidant site of human ceruloplasmin: A model for oxidative damage by copper bound to protein surfaces

Free transition metal ions oxidize lipids and lipoproteins in vitro; however, recent evidence suggests that free metal ion-independent mechanisms are more likely in vivo. We have shown previously that human ceruloplasmin (Cp), a serum protein containing seven Cu atoms, induces low density lipoprotei...

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Detalhes bibliográficos
Main Authors: Mukhopadhyay, Chinmay K., Mazumder, Barsanjit, Lindley, Peter F., Fox, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23532/
https://ncbi.nlm.nih.gov/pubmed/9326646
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