Identification of the prooxidant site of human ceruloplasmin: A model for oxidative damage by copper bound to protein surfaces
Free transition metal ions oxidize lipids and lipoproteins in vitro; however, recent evidence suggests that free metal ion-independent mechanisms are more likely in vivo. We have shown previously that human ceruloplasmin (Cp), a serum protein containing seven Cu atoms, induces low density lipoprotei...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23532/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11546 |
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