Identification of the prooxidant site of human ceruloplasmin: A model for oxidative damage by copper bound to protein surfaces

Free transition metal ions oxidize lipids and lipoproteins in vitro; however, recent evidence suggests that free metal ion-independent mechanisms are more likely in vivo. We have shown previously that human ceruloplasmin (Cp), a serum protein containing seven Cu atoms, induces low density lipoprotei...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Mukhopadhyay, Chinmay K., Mazumder, Barsanjit, Lindley, Peter F., Fox, Paul L.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1997
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23532/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11546
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