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A single in vivo administration of bombesin antagonist RC-3095 reduces the levels and mRNA expression of epidermal growth factor receptors in MXT mouse mammary cancers

Epidermal growth factor (EGF) and its receptors (EGFR) play important roles in tumorigenesis. In various experimental cancers, treatment with antagonists of bombesin/gastrin-releasing peptide (BN/GRP) produces a reduction in EGFRs, concomitant to inhibition of tumor growth. To investigate the mechan...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Szepeshazi, Karoly, Schally, Andrew V., Halmos, Gabor, Lamharzi, Najib, Groot, Kate, Horvath, Judit E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences of the USA 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC23529/
https://ncbi.nlm.nih.gov/pubmed/9380734
Tagiau: Ychwanegu Tag
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