Phosphorylation of two regulatory tyrosine residues in the activation of Bruton’s tyrosine kinase via alternative receptors

Mutation of Bruton’s tyrosine kinase (Btk) impairs B cell maturation and function and results in a clinical phenotype of X-linked agammaglobulinemia. Activation of Btk correlates with an increase in the phosphorylation of two regulatory Btk tyrosine residues. Y551 (site 1) within the Src homology ty...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wahl, Matthew I., Fluckiger, Anne-Catherine, Kato, Roberta M., Park, Hyunsun, Witte, Owen N., Rawlings, David J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23526/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326643/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11526
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!