Phosphorylation of two regulatory tyrosine residues in the activation of Bruton’s tyrosine kinase via alternative receptors

Mutation of Bruton’s tyrosine kinase (Btk) impairs B cell maturation and function and results in a clinical phenotype of X-linked agammaglobulinemia. Activation of Btk correlates with an increase in the phosphorylation of two regulatory Btk tyrosine residues. Y551 (site 1) within the Src homology ty...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wahl, Matthew I., Fluckiger, Anne-Catherine, Kato, Roberta M., Park, Hyunsun, Witte, Owen N., Rawlings, David J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC23526/
https://ncbi.nlm.nih.gov/pubmed/9326643
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