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Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression

Stimulation of antitumor immune mechanisms is the primary goal of cancer immunotherapy, and accumulating evidence suggests that effective alteration of the host–tumor relationship involves immunomodulating cytokines and also the presence of costimulatory molecules. To examine the antitumor effect of...

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Main Authors: Pützer, Brigitte M., Hitt, Mary, Muller, William J., Emtage, Peter, Gauldie, Jack, Graham, Frank L.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences of the USA 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC23520/
https://ncbi.nlm.nih.gov/pubmed/9380730
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