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Persistent Transcription of a Non-integrating Mutant of Simian Immunodeficiency Virus in Rhesus Macrophages
A non-integrating mutant, SIVsmD116N, was derived from the infectious pathogenic SIVsmE543-3 clone by introducing an Asp (D) to Asn (N) mutation into the catalytic domain of integrase. Although SIVsmD116N generated all viral proteins following transfection, cell free virus did not productively infec...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2350229/ https://ncbi.nlm.nih.gov/pubmed/18054062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.11.002 |
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