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Pathogenic role of cardiac mast cell activation/degranulation, TNF-α, and cell death in acute drug-related fatalities

BACKGROUND: Intravenous injection of narcotic stimulants affects many cellular functions relevant for the pathophysiological mechanisms of heart failure. There is considerable evidence that mast cells (MCs), TNF-α, and cell death play crucial roles in the pathogenesis and progression of cardiac arre...

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Bibliografiske detaljer
Main Authors: Perskvist, Nasrin, Söderberg, Carl, van Hage, Marianne, Edston, Erik
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2350147/
https://ncbi.nlm.nih.gov/pubmed/18200824
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