Enhancement of Hippocampal Pyramidal Cell Excitability by the Novel Selective Slow-Afterhyperpolarization Channel Blocker 3-(Triphenylmethylaminomethyl)pyridine (UCL2077)

The slow afterhyperpolarization (sAHP) in hippocampal neurons has been implicated in learning and memory. However, its precise role in cell excitability and central nervous system function has not been explicitly tested for 2 reasons: 1) there are, at present, no selective inhibitors that effectivel...

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Autores principales: Shah, Mala M., Javadzadeh-Tabatabaie, Mazyar, Benton, David C. H., Ganellin, C. Robin, Haylett, Dennis G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346772/
https://ncbi.nlm.nih.gov/pubmed/16877678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.106.026625
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