Variable Patterns of Programmed Death-1 Expression on Fully Functional Memory T Cells after Spontaneous Resolution of Hepatitis C Virus Infection

The inhibitory receptor programmed death-1 (PD-1) is present on CD8(+) T cells in chronic hepatitis C virus (HCV), but expression patterns in spontaneously resolving infections are incompletely characterized. Here we report that PD-1 was usually absent on memory CD8(+) T cells from chimpanzees with...

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Autors principals: Bowen, David G., Shoukry, Naglaa H., Grakoui, Arash, Fuller, Michael J., Cawthon, Andrew G., Dong, Christine, Hasselschwert, Dana L., Brasky, Kathleen M., Freeman, Gordon J., Seth, Nilufer P., Wucherpfennig, Kai W., Houghton, Michael, Walker, Christopher M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346765/
https://ncbi.nlm.nih.gov/pubmed/18337576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00060-08
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