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Toll-Like Receptor 9-Dependent Immune Activation by Unmethylated CpG Motifs in Aspergillus fumigatus DNA

Phagocytic defenses are critical for effective host defenses against the opportunistic fungal pathogen Aspergillus fumigatus. Previous studies found that following challenge with A. fumigatus, Toll-like receptor 9 (TLR9) knockout mice survived longer than wild-type mice. However, the mechanism respo...

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Detalhes bibliográficos
Main Authors: Ramirez-Ortiz, Zaida G., Specht, Charles A., Wang, Jennifer P., Lee, Chrono K., Bartholomeu, Daniella C., Gazzinelli, Ricardo T., Levitz, Stuart M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346696/
https://ncbi.nlm.nih.gov/pubmed/18332208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00047-08
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