Enhancement of Antibody Responses to Bacillus anthracis Protective Antigen Domain IV by Use of Calreticulin as a Chimeric Molecular Adjuvant

The generation of protective humoral immune responses against the receptor-binding domain (domain IV) of protective antigen [PA(dIV)] of Bacillus anthracis represents a plausible approach against anthrax toxin. In the current study, we have developed a naked DNA vaccine encoding calreticulin (CRT) l...

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Hlavní autoři: Park, Yong Sung, Lee, Jin Hyup, Hung, Chien-Fu, Wu, T.-C., Kim, Tae Woo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346671/
https://ncbi.nlm.nih.gov/pubmed/18285494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01722-07
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