Predictive Values of the Human Immunodeficiency Virus Phenotype and Genotype and of Amprenavir and Lopinavir Inhibitory Quotients in Heavily Pretreated Patients on a Ritonavir-Boosted Dual-Protease-Inhibitor Regimen

The inhibitory quotient (IQ) of human immunodeficiency virus (HIV) protease inhibitors (PIs), which is the ratio of drug concentration to viral susceptibility, is considered to be predictive of the virological response. We used several approaches to calculate the IQs of amprenavir and lopinavir in a...

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Detalhes bibliográficos
Main Authors: Barrail-Tran, Aurélie, Morand-Joubert, Laurence, Poizat, Gwendoline, Raguin, Gilles, Le Tiec, Clotilde, Clavel, François, Dam, Elisabeth, Chêne, Geneviève, Girard, Pierre-Marie, Taburet, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346619/
https://ncbi.nlm.nih.gov/pubmed/18285478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01314-07
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