AMPK α(1) Activation Is Required for Stimulation of Glucose Uptake by Twitch Contraction, but Not by H(2)O(2), in Mouse Skeletal Muscle

BACKGROUND: AMPK is a promising pharmacological target in relation to metabolic disorders partly due to its non-insulin dependent glucose uptake promoting role in skeletal muscle. Of the 2 catalytic α-AMPK isoforms, α(2) AMPK is clearly required for stimulation of glucose transport into muscle by ce...

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Autors principals: Jensen, Thomas E., Schjerling, Peter, Viollet, Benoit, Wojtaszewski, Jørgen F. P., Richter, Erik A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346549/
https://ncbi.nlm.nih.gov/pubmed/18461163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002102
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