Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

OBJECTIVE: Evidence for AMP-activated protein kinase (AMPK)-mediated regulation of skeletal muscle metabolism during exercise is mainly based on transgenic mouse models with chronic (lifelong) disruption of AMPK function. Findings based on such models are potentially biased by secondary effects rela...

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Publicado no:Mol Metab
Main Authors: Hingst, Janne R., Kjøbsted, Rasmus, Birk, Jesper B., Jørgensen, Nicolas O., Larsen, Magnus R., Kido, Kohei, Larsen, Jeppe Kjærgaard, Kjeldsen, Sasha A.S., Fentz, Joachim, Frøsig, Christian, Holm, Stephanie, Fritzen, Andreas M., Dohlmann, Tine L., Larsen, Steen, Foretz, Marc, Viollet, Benoit, Schjerling, Peter, Overby, Peter, Halling, Jens F., Pilegaard, Henriette, Hellsten, Ylva, Wojtaszewski, Jørgen F.P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356270/
https://ncbi.nlm.nih.gov/pubmed/32504885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101028
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