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A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery

BACKGROUND: Several human pathologies, including neoplasia and ischemic cardiovascular diseases, course with an unbalance between oxygen supply and demand (hypoxia). Cells within hypoxic regions respond with the induction of a specific genetic program, under the control of the Hypoxia Inducible Fact...

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Main Authors: Alcaide-German, Maria L, Vara-Vega, Alicia, Garcia-Fernandez, Luis F, Landazuri, Manuel O, del Peso, Luis
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346465/
https://ncbi.nlm.nih.gov/pubmed/18402654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-9-18
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