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Protein preparation, crystallization and preliminary X-ray analysis of the C-terminal domain of human RSK1 serine/threonine protein kinase

As a substrate of extracellular signal-related kinase (ERK), the p90 ribosome S6 kinase 1 (RSK1) is at the terminus of the Ras/ERK pathway. Residues 411–735 of human RSK1, covering the C-terminal serine/threonine kinase catalytic domain and the functionally important tail, were cloned into an Escher...

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Detalhes bibliográficos
Main Authors: Fu, Tian-Min, Li, Dan, Nan, Jie, Li, Lanfen, Xue, Yafeng, Su, Xiao-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2344107/
https://ncbi.nlm.nih.gov/pubmed/18084084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107051329
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