A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group

As glucocorticoid use increased in acute lymphoblastic leukemia, osteonecrosis became an increasingly frequent complication. Besides increased age, host risk factors are poorly defined. We tested whether 12 polymorphisms were associated with osteonecrosis among patients 10 years and older treated on...

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Main Authors: French, Deborah, Hamilton, Leo H., Mattano, Leonard A., Sather, Harland N., Devidas, Meenakshi, Nachman, James B., Relling, Mary V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Clinical Trials and Observations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343589/
https://ncbi.nlm.nih.gov/pubmed/18285546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-123885
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