Transforming growth factor-β(1) reduces megalin- and cubilin-mediated endocytosis of albumin in proximal-tubule-derived opossum kidney cells

Transforming growth factor (TGF)-β(1) is a member of a superfamily of multifunctional cytokines involved in several pathological processes of the kidney, including fibrogenesis, apoptosis and epithelial-mesenchymal transition. These events lead to tubulointerstitial fibrosis and glomerulosclerosis....

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Autori principali: Gekle, Michael, Knaus, Petra, Nielsen, Rikke, Mildenberger, Sigrid, Freudinger, Ruth, Wohlfarth, Verena, Sauvant, Christoph, Christensen, Erik I
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2003
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343374/
https://ncbi.nlm.nih.gov/pubmed/14561830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.048074
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