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Veratridine block of rat skeletal muscle Nav1.4 sodium channels in the inner vestibule

Veratridine (VTD) is an alkaloid toxin found in Liliaceae plants. VTD causes persistent opening of the voltage-gated Na(+) channel and reduces its single-channel conductance by 75 %. The mechanisms for these different VTD actions are unknown. Recent reports indicate that the VTD receptor aligns clos...

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Detalhes bibliográficos
Main Authors: Wang, Ging Kuo, Wang, Sho-Ya
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342907/
https://ncbi.nlm.nih.gov/pubmed/12626674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.035469
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