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Acute hypoxia occludes hTREK-1 modulation: re-evaluation of the potential role of tandem P domain K(+) channels in central neuroprotection

The human tandem P domain K(+) channel hTREK-1 (KCNK2) is distributed widely through the CNS. Here, whole-cell patch clamp recordings were employed to investigate the effects of hypoxia on hTREK-1 channels stably expressed in human embryonic kidney cells. Acute hypoxia caused a rapid and reversible...

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Detalhes bibliográficos
Principais autores: Miller, P, Kemp, P J, Lewis, A, Chapman, C G, Meadows, H J, Peers, C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342782/
https://ncbi.nlm.nih.gov/pubmed/12611912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.040048
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