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The lipid-activated two-pore domain K(+) channel TREK-1 is resistant to hypoxia: implication for ischaemic neuroprotection

TREK-1 is a member of the two-pore domain potassium (K(2P)) channel family that is mechano-, heat, pH, voltage and lipid sensitive. It is highly expressed in the central nervous system and probably encodes one of the previously described arachidonic acid-activated K(+) channels. Polyunsaturated fatt...

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Detalhes bibliográficos
Main Authors: Buckler, KJ, Honoré, E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665478/
https://ncbi.nlm.nih.gov/pubmed/15498799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.077503
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