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The actin cytoskeleton and cytotoxic T lymphocytes: evidence for multiple roles that could affect granule exocytosis-dependent target cell killing

One important mechanism cytotoxic T lymphocytes (CTLs) use to kill virus-infected, transplanted or tumour targets is exocytosis of granules that contain cytotoxic agents such as perforin and granzymes. Granule exocytosis-dependent target cell killing is a complex process, involving initial T-cell re...

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Detalhes bibliográficos
Main Authors: Lyubchenko, Taras A, Wurth, Georjeana A, Zweifach, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342722/
https://ncbi.nlm.nih.gov/pubmed/12576500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.033522
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