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β(2)-Adrenergic receptor polymorphism and nitric oxide-dependent forearm blood flow responses to isoproterenol in humans

Polymorphisms in the gene encoding the β(2)-adrenoceptor have been associated with interindividual differences in blood pressure and the diagnosis of hypertension. A common polymorphism resulting in a change from arginine to glycine at amino acid 16 (Arg16 → Gly) enhances agonist-promoted downregula...

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Bibliografische gegevens
Hoofdauteurs: Garovic, Vesna D, Joyner, Michael J, Dietz, Niki M, Boerwinkle, Eric, Turner, Stephen T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342525/
https://ncbi.nlm.nih.gov/pubmed/12527744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.031138
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