Arg16Gly polymorphism of the β(2)-adrenergic receptor is associated with differences in cardiovascular function at rest and during exercise in humans

In humans, subjects homozygous for arginine (ArgArg) at codon 16 of the β(2)-adrenergic receptor (β(2)AR) have been shown to have greater agonist-mediated desensitization than subjects homozygous for glycine (GlyGly). We sought to determine if this substitution differentially influenced cardiovascul...

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Detalhes bibliográficos
Main Authors: Snyder, Eric M, Beck, Kenneth C, Dietz, Niki M, Eisenach, John H, Joyner, Michael J, Turner, Stephen T, Johnson, Bruce D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805638/
https://ncbi.nlm.nih.gov/pubmed/16339181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.098558
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